1月12日 楊磊:Mechano-active biomaterials for tissue repair and regeneration


報告題目:Mechano-active biomaterials for tissue repair and regeneration

報告人:楊磊 河北工業大學

主持人:羅劍 教授

報告時間:2021年1月12日上午10:10(周二上午)

報告地點:生命科學學院534小會議室


報告人簡介:

楊磊,清華大學材料學學士、碩士,美國布朗大學工學博士、創新與創業管理碩士。歷任蘇州大學骨科研究所副所長、教授。現任河北工業大學健康科學與工程研究中心主任、教授。入選國家級海外人才項目及國家自然科學基金杰青、優青項目。近五年來在Nature Biomed Eng、Mater Today、Spine J、ACS Nano、Adv Funct Mater、Adv Sci 等期刊上發表論文40余篇;由Elsevier出版英文專著2部 ;申請中國發明30余項(授權13項)、美國授權發明2項。曾獲國際矯形與創傷外科學會SICOT基礎研究獎(全球每年1人)、中國創新創業大賽生物醫藥行業全國第二名、美國生物材料學會SFB博士生獎、美國Sigma Xi學會“全美125位青年學者獎”等。現任期刊Int J Nanomed(IF=5.115)副主編、中國材料研究學會青委會理事、中華醫學會骨科學分會創新與轉化學組委員、中國老年學和老年醫學學會骨科分會基礎學組副組長、國際矯形與創傷外科學會SICOT中國部骨科基礎學會常委、中國生物材料學會生物陶瓷分會委員、中國機械工程學會生物制造工程分會委員等學會任職。


報告內容:

There is a lack of effective tissue repair and regeneration strategies in current clinical practices. Numerous studies have suggested that smart or responsive biomaterials possessing the ability to respond to endogenous stimuli in vivo may positively mediate the tissue micro-environment towards a tissue repair or regeneration. Mechanical stimuli, which constantly exist in a wide range of biological systems and are involved in almost all the physiological processes, belong to such stimuli to which responsive biomaterials can respond. Based on recent studies, a new type of smart biomaterials has emerged that can dynamically adapt to the mechanical stimuli in vivo and thus has specific functionality consistently mediated by such mechanical stimuli. In contrast to common biomaterials that only passively react to the mechanical environment of an implantation site, such mechano-active biomaterials have enabled various active or automatic strategies for tissue repair or regeneration, such as providing precise spatial-temporal controls on delivery of drugs or cells in the organs of the musculoskeletal and the circulatory systems; in situ reconstructing the original or a favorable mechanical environment at a lesion site; and accelerating the tissue remodeling or healing process via a mechanobiological effect. This talk elucidates a perspective of perfecting tissue repair or regeneration using mechano-active biomaterials, especially highlighting the rationale behind the concept of mechano-active biomaterials and their potential in the repair or regeneration of musculoskeletal and cardiovascular tissues.


彩神-入口